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# Specific Standards

HTAN Centers submit assay data files and metadata to HTAN. HTAN's Data Models govern how the assay data is organized and what metadata accompanies the assay data. The data model changed in HTAN Phase 2.

Example HTAN Metadata and Assay Data
Example HTAN Metadata and Assay Data

For HTAN Phase 1, The HTAN Portal's Data Standards pages provide interactive, searchable and downloadable summaries of the metadata attributes, requirements and valid values expected for each data type.

# Phase 1 Table of Specific Standards

Category Specific Standard
Biospecimen Biospecimen
Clinical Demographics
Clinical Diagnosis
Clinical Exposure
Clinical Family History
Clinical Follow Up
Clinical Molecular Test
Clinical Participant Vital Status Update
Clinical Therapy
Clinical Clinical Data Tier 2
Clinical Acute Lymphoblastic Leukemia Tier 3
Clinical Breast Cancer Tier 3
Clinical Colorectal Cancer Tier 3
Clinical Lung Cancer Tier 3
Clinical Melanoma Tier 3
Clinical Ovarian Cancer Tier 3
Clinical Pancreatic Cancer Tier 3
Clinical Pancreatic Cancer Tier 3
Clinical Prostate Cancer Tier 3
Clinical Sarcoma Tier 3
Imaging Imaging Level 1
Imaging Imaging Level 2
Imaging Imaging Level 3
Imaging Imaging Level 4
Mass Spectrometry Mass Spectrometry Level 1
Mass Spectrometry Mass Spectrometry Level 2
Mass Spectrometry Mass Spectrometry Level 3
Mass Spectrometry Mass Spectrometry Level 4
Mass Spectrometry Mass Spectrometry Auxiliary File
Proteomics RPPA Level 2
Proteomics RPPA Level 3
Proteomics RPPA Level 4
Sequencing Bulk DNA Level 1
Sequencing Bulk DNA Level 2
Sequencing Bulk DNA Level 3
Sequencing Bulk Methylation-seq Level 1
Sequencing Bulk Methylation-seq Level 2
Sequencing Bulk Methylation-seq Level 3
Sequencing Bulk RNA-seq Level 1
Sequencing Bulk RNA-seq Level 2
Sequencing Bulk RNA-seq Level 3
Sequencing Hi-C-seq Level 1
Sequencing Hi-C-seq Level 2
Sequencing Hi-C-seq Level 3
Sequencing scATAC-seq Level 1
Sequencing scATAC-seq Level 2
Sequencing scATAC-seq Level 3
Sequencing scATAC-seq Level 3
Sequencing scDNA-seq Level 1
Sequencing scDNA-seq Level 2
Sequencing scmC-seq Level 1
Sequencing scmC-seq Level 2
Sequencing scRNA-seq Level 1
Sequencing scRNA-seq Level 2
Sequencing scRNA-seq Level 3
Sequencing scRNA-seq Level 4
Spatial Transcriptomics 10X Genomics Xenium ISS Experiment
Spatial Transcriptomics 10x Visium Spatial Transcriptomics - RNA-seq Level 1
Spatial Transcriptomics 10x Visium Spatial Transcriptomics - RNA-seq Level 2
Spatial Transcriptomics 10x Visium Spatial Transcriptomics - RNA-seq Level 3
Spatial Transcriptomics 10x Visium Spatial Transcriptomics - Auxiliary Files
Spatial Transcriptomics Nanostring CosMx SMI Experiment
Spatial Transcriptomics NanoString GeoMx DSP ROI DCC Segment Annotation Metadata
Spatial Transcriptomics NanoString GeoMx DSP ROI RCC Segment Annotation Metadata
Spatial Transcriptomics NanoString GeoMx DSP Spatial Transcriptomics Level 1
Spatial Transcriptomics NanoString GeoMx DSP Spatial Transcriptomics Level 3
Spatial Transcriptomics Slide-seq Level 1
Spatial Transcriptomics Slide-seq Level 2
Spatial Transcriptomics Slide-seq Level 3

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